Carbohydrate Chemistry

Azides in Carbohydrate Chemistry

The fi rst az.ide-contain ing sugar, a glycosyl azide. was reponed in 1930 by Bertho. j Since that lime various methods have been developed for the introduction of azides at d ifferent positions of sugars. A survey of available methods is given in Section 16.2. Unlillhc lale I 970s, azidcs contai ned in carbohydrate deri vatives were simply used as accessible syn-thons [or amities because of th...

Food Carbohydrate Chemistry

The reactions of sugars that are critical in food science applications can be organized into a few general types of reactions that are heavily influenced by pH. Although there are a few exceptions, most of these reactions occur under the relatively mild conditions that prevail during processing and storage. This chapter will not address reactions of chemical synthesis and sugar structure proof....

Essentials in Carbohydrate Chemistry andBiochemistry

Protecting groups in carbohydrate chemistry: influence on stereoselectivity of glycosylations.

Saccharides are polyhydroxy compounds, and their synthesis requires complex protecting group manipulations. Protecting groups are usually used to temporarily mask a functional group which may interfere with a certain reaction, but protecting groups in carbohydrate chemistry do more than protecting groups usually do. Particularly, protecting groups can participate in reactions directly or indire...

Bifunctional dendrons for multiple carbohydrate presentation via carbonyl chemistry

The synthesis of new dendrons of the generations 0, 1 and 2 with a double bond at the focal point and a carbonyl group at the termini has been carried out. The carbonyl group has been exploited for the multivalent conjugation to a sample saccharide by reductive amination and alkoxyamine conjugation.